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The evidence: In people with health conditions that cause a vitamin B deficiency or result in hair loss or brittle nails, limited research suggests that biotin supplements may help

The synthesis constitutes a formal total synthesis, since the research groups only prepared the known intermediate cobyric acid, whose chemical conversion to vitamin B 12 was previously reported

Other Articles Ferrarotto, R, Amit, M, Nagarajan, P, Rubin, ML, Yuan, Y, Bell, D, El-Naggar, AK, Johnson, JM, Morrison, WH, Rosenthal, D , Glisson, BS, Johnson, FM, Lu, C, Mott, FE, Esmaeli, B, Diaz Jr, EM, Gidley, PW, Goepfert, RP, Lewis, CM, Weber, RS, Wargo, J, Basu, S, Duan, F, Yadav, SS, Sharma, P, Allison, JP, Myers, JN, Gross, N Erratum

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