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Cell death pathways in pancreatitis and pancreatic cancer

Strategies aimed at restoring glutathione homeostasis or reducing oxidative and inflammatory stress could also be explored as possible complements to existing TTR-targeted therapies

Therefore, PIP2 may function in defining the local concentration of nuclear RDPA proteins and regulating their localization and condensation capacity as suggested in (55)

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Br J Pharmacol 136:659672 Rosenbrock H, Desch M, Kleiner O, Dorner-Ciossek C, Schmid B, Keller S, Schlecker C, Moschetti V, Goetz S, Liesenfeld KH, Fillon G, Giovannini R, Ramael S, Wunderlich G, Wind S (2018) Evaluation of pharmacokinetics and pharmacodynamics of BI 425809, a novel GlyT1 inhibitor: translational studies