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10.1007/s11033-018-4323-4 503

10.2147/DDDT.S218708 Drug Des

Pharmacological activation of AMPK has been successful in alleviating mitochondrial dysfunction and ER stress conditions (Li et al., 2015[84])

Both substances are recommended by guidelines for the prophylaxis of certain radiation-induced side effects [4, 10]

FIGURE 1 Conclusion and future perspective In inflammatory conditions of IBD, the migration of inflammatory cells into the colon, such as neutrophils, results in the production of oxidative stress, ROS, and lipid peroxidation