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BPC 157 inhibits K+ conductance in WT HEK293 cells J Physiol Pharmacol 2009

b , Chemical structures of TCA and DHEAS

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The amyloid-related pathology can be associated with two deleterious mechanisms: (i) the inability of the amyloid-forming protein to perform its native function, termed as loss of function mechanism and (ii) the amyloid deposit itself is to the cellular metabolism, referred as toxic gain of function (Winklhofer et al., 2008)