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Also, hormonal changes that occur at certain stages of life, such as menopause in women, can cause collagen breakdown, dryness, sagging skin and wrinkles, but also greater bone porosity and joint sensitivity

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It represents a low dose prophylactic nasal spray that, according to recent literature on niclosamide and viruses, could stop virus replication at its point of entry in the nose, and a higher concentration throat spray, that could reduce viral load as it progresses down the back of the throat

This also contributes to prolonged drug elimination and increased risk of toxicity and drug-drug interactions, as multiple drugs may compete for the same excretion sites