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Complete supply calculation for a 16-week protocol Weeks 1-4 (2mg/week): 2mg x 4 weeks = 8mg total Weeks 5-8 (4mg/week): 4mg x 4 weeks = 16mg total Weeks 9-12 (8mg/week): 8mg x 4 weeks = 32mg total Weeks 13-16 (12mg/week): 12mg x 4 weeks = 48mg total Grand total: 104mg over 16 weeks Now translate that into vials: Using 10mg vials exclusively: 104mg / 10mg = 10.4 vials

doi: 10.1146/annurev-food-041715-033159 49 ZhengXHuangFZhaoALeiSZhangYXieGet al

Kim J, Lee HJ, Park JH, Cha BY, Hoe HS

In this section of this proposed rule, we discuss the data sources and methodologies for computing each of these factors, our final policies for FYs 2014 through 2023, and our proposed policies for FY 2024

The clinical spectrum is wide