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As a typical amphiphilic structure, LNPs can simultaneously load both hydrophilic and hydrophobic drugs, thereby mimicking natural cell membranes and significantly enhancing cellular uptake and endocytosis processes (45)

A deeper understanding of these interconnected pathophysiologic mechanisms will facilitate the development of targeted therapies beyond cysteamine, optimizing treatment approaches to mitigate disease progression [146]

A recombinant GSTP1-1 and glutathione were added to a DNAT-Me (200 M) solution in a quartz cuvette, and fluorescence emission spectra were measured from 470 to 600 nm with excitation at 488 nm

Lumbar Disc Degeneration Is Linked to a Carbohydrate Sulfotransferase 3 Variant

Increased carnitine-dependent fatty acid uptake into mitochondria of human colon cancer cells induces apoptosis