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As melanoma develops, it exhibits adaptive responses to the high levels of ROS

PAL exhibits strong inducibility under stress conditions, enhancing the synthesis of all phenolic compounds, including phytoalexins, thereby serving as a primary adaptive response to a number of biotic and abiotic stressors [177]

Brault, S

For lower extremity arteriosclerosis obliterans, drug-coated devices locally release anti-proliferative agents, significantly improving revascularization outcomes in femoropopliteal artery lesions ( 4.9 Modern research on traditional Chinese medicine Traditional Chinese medicine (TCM) compounds, such as Qingmai Yin and Simiao Yongan Tang, demonstrate significant efficacy in improving arteriosclerosis obliterans in clinical practice, highlighting TCMs holistic multi-component, multi-target regulatory advantages

Both coffee (Reference Ludwig, Clifford and Lean2) and tea (Reference Khan and Mukhtar3) contain several beneficial components including polyphenols such as lignans and chlorogenic acid and epigallocatechin gallate, which are believed to be associated with a lower risk of site-specific cancers, CVD and premature death (Reference Poole, Kennedy and Roderick4,Reference Yi, Wu and Zhuang5)