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Moreover, the arsenite-induced occurrence of sister chromatid exchanges is reduced by SOD in cultured human lymphocytes [16]

8 Local anaesthetics also have a toxic effect on muscle cells, with greater damage again linked to higher concentrations and exposure

Using genetic and pharmacological approaches in yeast, mammalian cells and Drosophila , we found that GPx activity robustly ameliorates Huntington's diseaserelevant metrics and is more protective than other antioxidant approaches tested here

Dox pretreatment alone delayed the onset of ferroptosis (i.e., increased D O ) in response to erastin2 in Control cells capable of expressing p21, albeit not to the same extent as nutlin-3 treatment (Fig 2B and C)