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Melatonin also modulates aspects of sickness behaviors [139], inhibiting NFB induction and microglia activation [140], suggesting that variations in melatonin may confound the comparison of processes in ME/CFS and sickness behavior

Results: UMAP dimensionality reduction and density-based clustering identified 44 clusters of cells

3,4,5 The involvement of NF-B in inflammation and immune responses is indisputable, and this is the most important role that NF-B signaling plays in biology