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J Vet Med Sci 2016;78:957-62.ArticlePubMedPMC 73

Link Murai, S., et al

Anyone with known renal impairment should calculate washout periods using a 10-day half-life rather than the standard 7-day estimate

These models allow for transmigration studies as well as more precise measurements of TEER making them very useful in permeability studies and reduces the number of cells needed for the model [117]