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Statistical analysis Analysis set Analysis populations are defined as follows: 1) Intention to treat (ITT): this population includes all randomized participants regardless of whether they were later found to be ineligible, did not adhere to the protocol or were never treated

in Nature Medicine demonstrated that blocking NNMT in white adipose tissue increased energy expenditure, reduced fat mass, and improved insulin sensitivity in animal models even without changes in diet or activity (Kraus et al., Nature Medicine )

The most common side effect is some pain at the injection site

My toes burned in my shoes