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Oxidative stress impairs SIRT3 activity and transcription by regulating protein carbonylation and transcriptional function of peroxisome proliferator-activated receptor- coactivator-1, leading to mitochondrial dysfunction and activation of the mitochondrial apoptotic pathway via optic atrophy 1 to induce cell death of vitiligo melanocytes [32]

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promotes collagen production, protects the skin against the harmful effects of UV rays, prevents wrinkles from forming

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Your body produces them naturally, and they act as signalling molecules, telling different systems what to do and when to do it