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Evolution of white matter damage in amyotrophic lateral sclerosis

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In the spinal nerve ligation model, in which anatomic nerve regeneration can be easily observed, nicotine reduced anatomic measures of regeneration as well as expression of regeneration marker growth-associated protein 43 (GAP43)

For BODIPY 493/503 staining, samples were incubated with 2 M BODIPY 493/503 (1 ml/well) for 30 min at RT

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