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At 0, 3, 7, and 10 days, the tissues were fixed, and cryosections were used for in situ apoptotic staining with terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL), according to the manufacturers instructions (Servicebio, Beijing, China)

[PMC free article] [PubMed] [Google Scholar] Thomas DJ, Styblo M, Lin S

Tengholm, A

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This allows for the development of targeted drug delivery systems that can accumulate at tumor sites, enhancing drug efficacy while reducing systemic side effects