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Since the synthesis of AA-CoA by ACSL4 is the first step in the incorporation of AA into PLs, the inhibition or overexpression of ACSL4 could modulate the proportion of PL-AA in cell membranes

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In individuals with diabetes, careful attention to glycemic control is necessary, including monitoring blood glucose levels before and after training sessions and timing exercise to avoid periods of peak insulin activity (KANALEY et al., 2022)