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Time Frames: From baseline (week 0) to end of treatment (week 64)

Its ability to affect thousands of genes, induce collagen formation, contribute to tissue repair, and accelerate wound healing makes it a subject of intense interest in both anti-aging and regenerative studies

For B12 to be absorbed, it requires a protein called intrinsic factor (IF)

Additionally, the expanding wellness and anti-aging sectors are contributing to market expansion as consumers seek effective solutions for enhancing overall vitality

Therefore, an increased supply of Met may increase antioxidant production, potentially aiding in the relief of oxidative stress and inflammation triggered by the production of reactive oxygen metabolites ( Conversely, Hcy has the capacity for remethylation to regenerate methionine, which relies on the folate cycle and vitamin B 12 ( Figure 1 ) ( 2 -THF), which is subsequently reduced to 5-methyltetrahydrofolate (5-CH 3 -THF) (Preynat et al., 2009)