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The evaluated LRTs for CCA involve thermal ablation, including radiofrequency ablation and microwave ablation, external beam radiotherapy, or transarterial treatments such as transarterial chemoembolization (TACE), selective internal radiation therapy (SIRT

While tissue biopsy techniques enable direct observation of cell proliferation (CPx), differentiation, and extracellular matrix (ECM) synthesis, inconsistent operational protocols (OPs) for sampling locations (SLs), frequency, and analytical methods (AMs) create protocol variability (PV)

Annals of the American Thoracic Society, 13 (Suppl 5), S422-S428

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