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This "unlocks" silenced genes associated with protein synthesis and cellular repair

The adverse effects were minimal in wildtype mice fed with safflower oil

J.McFadyen-KetchumL.SolakS.WuH.LevittP

Mechanistically, GHK-Cu appears to act through several pathways: Collagen and elastin remodeling: Gene array work by Finkley et al., reported in the second edition of Cosmeceuticals and Active Cosmetics (Taylor and Francis, 2005), examined GHK-Cu effects on human fibroblast cultures across a nanomolar to low micromolar concentration range and found upregulation of decorin, collagen, and elastin-associated genes

Proceedings of the American Academy of Dermatology Meeting (2002) 6