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Overview of the Sulfur Assimilation, Cysteine Biosynthesis, and Download Scientific Diagram Cysteine is the substrate for the intracellular synthesis of Download Scientific Diagram Glutathione Depletion Pathways 1. Precursor Depletion Key bottleneck: Cysteine availability. Source: Diet or hepatic transsulfuration (methionine homocysteine cysteine). Failure mode: Downregulation of cystathionine lyase (CSE) during Managing Competing Interests: Partitioning S between Glutathione and Protein Synthesis Plantae GSH hoards all the cysteinewhat a slimy thing to do Nature Metabolism
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