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ROS damage the mitochondria of dermal papilla cells, disrupt the ECM, accelerate collagen degradation, and impair the DNA repair mechanisms that keep follicular stem cells healthy and functionally active

This overproduction often shows up as dark patches, uneven tone, or spots

Excessive caffeine intake can also interfere with the effectiveness of glutathione

Glutathione has been defined as a "xenobiotic toxicity defense agent," meaning that it protects against the harms of taking drugs, environmental pollutants, or carcinogens

Dented or raised = true scars, which need collagen rebuilding and, if deep, professional care