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Here, we employed comparative global metabolomics to demonstrate that metabolism of the antioxidant glutathione (GSH) is inextricably linked to redox-active processes that facilitate melanin production, and that genetic perturbations in GSH biosynthesis affect fungal growth and virulence in a murine model of cryptococcosis

Interestingly, while Epothilone B was identified as a P-glycoprotein substrate, the glutathione-epothilone conjugate was not, suggesting potential differences in cellular retention

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Effect of chemotherapy on primordial follicular reserve of rat: an animal model of premature ovarian failure and infertility

J Physiol Pharmacol 59:251264 Eley HL, Tisdale MJ (2007) Skeletal muscle atrophy, a link between depression of protein synthesis and increase in degradation