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248 A small number of clinical studies have found that antioxidant vitamin E, CoQ10, and alpha-lipoic acid combined with polarized light are effective in controlling T2DM complications, including diabetic foot

Under hypoxic conditions, lactate could enter fibrogenic mesenchymal progenitor cells through the GPR81 receptor to enhance their self-renewal, intensified by HIF-1 augmenting GPR81 expression [180]