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2.12 GO and KEGG enrichment analysis of differentially expressed genes GO, including biological processes (BP), cellular components (CC), and molecular functions (MF), KEGG enrichment analysis, and visualisation of DEmRNAs were performed using the R-packages clusterProfiler, org.Hs.eg.db, enrichplot, and ggplot2 with p -value thresholds of 0.05)

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