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Both activators create a heterodimer, which inhibits the transcription of repressor proteins Period 2 (PER2) and cryptochrome (CRY) that regulates the daily rhythms of locomotor activity, metabolism and behaviour [114]

Four capsules per day

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Informed consent was obtained from each patient who agreed to participate in the study

This perspective reframes ASD not solely as a neurodevelopmental disorder, but as a metabolically guided systems condition , in which neural, immune, and gut-brain axes are modulated by shifts in mitochondrial and folate signaling