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For the MOTS-c 5-amino-1MQ stack protocol, researchers commonly administer MOTS-c subcutaneously three to five times per week, often timed around fasted training sessions or periods of caloric restriction to maximize AMPK activation

Pharmacol Biochem Behav 46(2):477481 Hellevuo K, Kiianmaa K (1989) GABA turnover in the brain of rat lines developed for differential ethanol-induced motor impairment