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reported that the synthetic iron chelator [5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline] (M-30) , which permeates the BBB and reduces cellular APP and A production levels, was shown to alleviate the intellectual disability in mice after AD in an in vivo animal model (Zhang et al., 2022)

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NMN (-Nicotinamide Mononucleotide) is a direct precursor to NAD+, a vital coenzyme involved in cellular energy production and essential biological processes

Academic and employment challenges arise due to frequent hospitalizations and treatment burden