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Upon internalization, biological processing of a suitably designed linker would release the nuclear hormone and allow activation of its intracellular receptor

Its the subject of ongoing studies

In these trials, patients who were overweight or obese, with and without T2DM, with or without antidiabetic medications, were allocated in groups which received semaglutide in two different dosages (0.5mg or 1.0mg) or placebo or another anti-diabetic therapy

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