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To a solution of L28A-2 (480 mg, 1.4 mmol) in DCM (15 mL) and pyridine (2 mL) at 0 C

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While brief palpitations are often harmless, they should not be ignored if they are frequent or accompanied by chest pain, fainting, dizziness, or shortness of breath

To optimize the bioavailability of systemically targeted inhaled drugs with favourable aerodynamic properties, dry powder aerosols have been engineered as large porous particles, thereby simplifying inhaler design 103,104,105