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Description

MTHFR has two forms, heterozygous or homozygous

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Key Takeaways: GSH depletion in Type 2 Diabetes is driven by impaired synthesis, not just increased oxidative consumption

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10.1006/abbi.1994.1105 Arch

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BH 4 is synthesized from its precursor GTP, with GCH1 acting as the rate-limiting enzyme

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This observation is supported by the results presented in Figs

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