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Furthermore, a retrospective cohort study showed that MET improved the sputum culture conversion rate among cavitary pulmonary TB patients with diabetes (258)

For instance, berberine, a natural compound, downregulates the expression of SLC1A5 in Hep3B and BEL-7404 cells, inhibiting Gln uptake and consequently suppressing expansion of liver cancer cells and tumor progression in vivo (77)