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This modulation of the signaling cascade can substantially influence cell migration and potentially lead to the development of resistance to paclitaxel in breast cancer cells

Several studies have determined that thymosin beta-4 increases the production of vascular endothelial growth factor (VEGF)

Funding This work was partially supported by the CONFAP 2023 mobility program, funded by Fundao de Amparo Pesquisa do Estado do Rio Grande do SUL (FAPERGS), number 83825.834.14145.28032024

Western blots Cell lysates and supernatants (reduced and denatured) were separated on 412% gradient gels (Invitrogen), proteins transferred onto nitrocellulose membrane (Amersham), and ponceau staining performed routinely to evaluate loading accuracy