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Its preliminary, but you can see that countries that have more ergothioneine in their diets, countries like France and Italy, also have lower incidences of neurodegenerative diseases, while people in countries like the United States, which has low amounts of ergothioneine in the diet, have a higher probability of diseases like Parkinsons Disease and Alzheimers, Beelman said

& Luo, H

For example, in the acidic environment of the stomach, glutathione's chemical bonds may be broken, rendering it partially inactivated before it reaches the intestinal absorption site

which contributes to oxidative stress in rat kidney cortex

It may shield the liver from injury due to toxins like alcohol and certain medications