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However, due to its moderate cholesterol-lowering effect, QT interval prolongation, and insufficient clinical evidence for cardioprotective effects, probucol has not achieved widespread clinical adoption

This widespread insufficiency provides a logical rationale for choline supplementation: correcting a common dietary gap may help restore normal fat-processing function in the liver

Degradation occurs in lysosome Defect in degradative enzymes leads to storage disorder of mucopolysaccharides in lysosome, called mucopolysaccharidosis

Oh, and one more nice thing: even though its synthetic its highly biodegradable

It is also most useful in the maintenance of the nervous system, assisting memory and learning