This can cause severe liver damage, leading to a condition known as acute liver failure
This discrepancy may reflect the multifactorial origin of cardiovascular damage, including endothelial and microvascular injury, persistent immune dysregulation, and RAAS imbalance that may not be adequately addressed by vaccine-induced systemic immunity
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ISG expression is also quantified in PBMCs using the NanoString technology (74 ISGs), with data being analyzed for gene expression relative to housekeeping genes