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In GF mice, thymic epithelial cells exhibit reduced Aire expression, which can be restored by colonization with specific gram-positive bacteria, suggesting that microbial cues are required for proper T-cell clonal selection [61, 62]

Found abundantly in red meat, carnitine is stored in skeletal muscles where it is needed to transform fatty acids into energy.

Spatial transcriptomics can localize pathway activation status in situ , delineating the spatial co-localization network of metabolic reprogramming, angiogenesis, and immune exclusion

Enzyme-Linked Immunosorbent Assay (ELISA) in Brain Tissues ELISA kit purchased from MyBioSource (Southern California, San Diego, USA) was used for the estimation of the brain content of glutamate (Cat

Consequently, it was determined an effective strategy through improvement of oridonin by liposome-MAL preparation