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Adding paragraph (b)(2)(vi)

The disease mechanism centers on disrupted equilibrium between tissue breakdown and rebuilding within the disc, causing deterioration of the extracellular matrix, depletion of proteoglycans and hydration, decreased disc height, and compromised mechanical stability

CAT specifically downregulated alanine aspartate and glutamate metabolism, and biotin metabolism among several highlighted pathways

Further investigations into the optimal dosage and targeting mechanisms of NMN are crucial to explore its therapeutic effects more comprehensively

Daily use is recommended for noticeable skin-brightening effects