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AUC is somewhat cumbersome to calculate in clinical context, and thus trough levels are frequently used as a surrogate

And bacterial contamination becomes a risk once preservatives in the solution begin to degrade, which happens faster at higher temperatures

It is the most common large joint dislocation, particularly affecting athletes and physically active individuals

This approach improved the stability of BSC spectrum-based measurements by avoiding artifactual effects of layered interfaces 30

The math is not complicated, but getting it wrong means the difference between an effective protocol and weeks of wasted time