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Moreover, about 3-fold slower CL and 3-fold longer MRT were calculated for the QMP-engineered fusions compared to GLP-1 WT (Supplementary Table 4)

Another study has shown that hepatocyte-conditional NIK deficiency alleviates nonalcoholic steatohepatitis (NASH), which involves a mechanism that is independent of NF-B but involves attenuation of JAK2-STAT5 signaling axis [28]