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Effect of melatonin supplementation on cardiometabolic risk factors, oxidative stress and hormonal profile in PCOS patients: a systematic review and meta-analysis of randomized clinical trials

ROS generation induced by HCV infection triggers anti-3-hydroxysterol 24-reductase (DHCR24) antibody production, suggesting that DHCR24 may be used as a prognostic biomarker for hepatitis C progression to hepatocellular carcinoma 56,97

Mitochondrial Ca 2+ overload due to MCU overactivation increases Ca 2+ sensitivity, enhancing myosin light chain phosphorylation and promoting contraction, and mitochondrial ROS activate redox-sensitive pathways such as MAPK and NF-B, driving VSMC proliferation and neointima formation

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