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Those with active cancer should consult an oncologist, as growth-factor modulation could theoretically influence tumor growth

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(Doctoral dissertation, Kenyatta University)

The reduced amounts of FMN and FAD will in turn reduce the activity of the enzyme MTRR and so the levels of inactive Co(II)B12 will build up inside the cell and will eventually be discarded from the cell resulting in a build up of Co(II)B12 in serum

Pour ces raisons, il est ncessaire deffectuer des analyses sanguines avant toute supplmentation et de respecter les doses recommandes, c'est--dire un maximum 14 mg pour une consommation sans risques