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Moreover, carotenoids that do not function as substrates (e.g., canthaxanthin, zeaxanthin) interfere with retinol conversion (by inhibiting carotene dioxygenase), whereas protein-energy malnutrition hampers retinol circulation (by affecting plasma levels of retinol-binding protein)

The following represents key Coding Clinic positions relevant to diabetes mellitus as of the most recent published guidance (4Q 2023 through 2025): Long-Term Insulin Use with Type 2 Diabetes Coding Clinic has consistently affirmed that when a Type 2 diabetic patient uses long-term insulin, coders must assign Z79.4 (long-term current use of insulin) as an additional code