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One of the better characterized metabolic phenotypes present in tumor cells is the Warburg effect, which gives preference to ATP generation through glycolysis, even under normal oxygen concentrations, over ATP synthesis through the electron transport chain in the mitochondria (Warburg, 1956

This adds to existing research on the role of dopamine in mediating immune response, which is evidenced by the synthesis of dopamine within, and expression of dopamine receptors on, immune cells (Channer et al., 2023

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doi: 10.3389/fvets.2021.621732 Received 26 October 2020 Accepted 25 January 2021 Published 18 February 2021 Volume 8 - 2021 Edited by Nora Mestorino, National University of La Plata, Argentina Reviewed by Pieter Annaert, KU Leuven, Belgium