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Moreadith and Lehninger, 1984

doi: 10.1038/s41598-017-12977-1 217 XuD

Chemodynamic therapy is a new anticancer approach in which agents (e.g., nanozymes) are used to convert hydrogen peroxide (H 2 O 2 ) into damaging hydroxyl radicals ( OH) via a Fenton reaction (Wang et al

Furthermore, ferroptosis can hinder neutrophil function by decreasing their capacity to eliminate infections and engage in phagocytic activity

Thus, first, a drug should be influxed from the blood to the brain capillary endothelial cells via a luminal uptake transporter and subsequently effluxed to the brain ECF via an abluminal transporter