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In summary, this review has identified several natural productssuch as Withania somnifera , Ocimum sanctum , curcumin, and Astragalus membranaceus that have demonstrated significant effects on thyroid function or pathology in preclinical models, with some like Astragalus and Dioscorea nipponica showing promise in preliminary clinical studies

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There is evidence in humans that iron accumulates in the RPE with age and in drusen and Bruchs membrane in early dry AMD, where chelatable iron is detected [19]

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