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Published 2021 May 16

The redox and metabolism adaptations to the high oxidative stress environment in cancer cells [1] are manifested by the higher levels in the TNBC cells of the anti-oxidant molecules, GSH and NADPH, the latter which is a major source of reducing equivalent

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Targeting PKM2 signaling cascade with salvianic acid A normalizes tumor blood vessels to facilitate chemotherapeutic drug delivery

GRC reduced splenic neutrophil and macrophage infiltration and increased the proportions of CD4 + and CD8 + T cells