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PMID 4152527

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Finally, they found that all three subregions inhibited the in vitro migration of TGF-activated human monocytes

Recent evidence suggests systemic therapy, either targeted agents or immunotherapy, can be effective in combating BrMs, especially those originating from well-characterized primary tumors ( The establishment of metastatic cancer encompasses entering the central nervous system (CNS) from the blood and crossing the BBB ( Recent accumulating evidence suggests that B cells play a multifaceted and relatively underexplored role in shaping the BrM tumor microenvironment (TME)