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Consistent with these metabolite levels, a HF-SAAR diet prompted a rise in the 13 C-labeling of liver serine and glycine in WT mice intravenously infused with [U- 13 C]glucose (Fig

Findings from these investigations, particularly those involving natural NAD + precursors, have reached the first clinical testing

Am J Physiol Lung Cell Mol Physiol 292:L1590L1597

Gaglio D, Metallo CM, Gameiro PA, Hiller K, Danna LS, Balestrieri C, Alberghina L, Stephanopoulos G, Chiaradonna F

Summary Keywords allergic asthma, immunometabolism, innate immunity, innate lymphoid Cells (ILC2), pentose phosphate pathway, redox homeostasis and signaling, respiratory immunology Citation Cain J, Hurrell BP, Shen S, Speliakos P and Akbari O (2026) Melatonin suppresses ILC2-driven airway hyperreactivity via glutathione-dependent metabolic reprogramming