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52 Gap-junction-mediated signalling between astrocytes and MDA-MB-231 cells also upregulates the expression of IL-6 and IL-8, leading to an increase in the production of endothelin-1 (ET-1) from astrocytes and the expression of the ET receptor on the tumour cells

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In contrast, treatments that increase the expression of the heavy subunit alone such as insulin, hydrocortisone in cultured hepatocytes and ethanol feeding in vivo , had no influence on the expression of GS