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These models can employ plasmid or mRNA-delivered transgenes, and/or CRISPR/Cas elements to enable more rapid recapitulation of mutations in diverse spatiotemporal contexts but have been mostly employed to generate HGG models (120123)

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Prevalence of anti-N-methyl-D-aspartate (NMDA) receptor [corrected] antibodies in patients with schizophrenia and related psychoses: a systematic review and meta-analysis

application of a targeting/internalization ligand avoids the need to apply polyplex systems with a large N/P ratio and therefore a high overall positive charge and may therefore reduce many problems that are associated with cationic polymers (such as toxicity, binding to blood constituents)

[DOI] [PMC free article] [PubMed] [Google Scholar] 156.Abe H, Aida Y, Seki N et al